How to handle my leopard gecko?

I've had my leopard gecko for at least 2 months now. I take great care of him, but I honestly don't think he likes me. I'm not sure how old he is, but he's grown since I bought him and he was really young then. He's already started getting paler and has many spots already. I've handled him a few times when I first got him but one day he decided to hiss at me. Last time I held him when I was cleaning his cage, he jumped out of my hands and hissed again. He hasn't bit me, I want to avoid that if possible.